Tianeptine: The Smart Drug for Your Mood

Tianeptine isn’t playing around. While other nootropics claim to provide you with a host of different positive benefits, tianeptine focuses on one benefit, and one benefit alone: mood enhancement.

It’s most commonly used to treat depression ranging from mild to severe. It’s actually been around since the 1960s, but because research on it was initially conducted exclusively in French, it took a while for it leave France. Now, it’s popular in the EU, and it’s becoming more popular in the US every single year.

Below, we’ll go over what you need to know about tianeptine including effects, dosing, and more. If you suffer from depression or you just want to feel better every day, you’re going to want to pay attention.

How tianeptine makes you feel good

This isn’t a “magical pill” – there have been studies conducted to observe how users react to the drug. Although we don’t know what exactly occurs in your body when you take tianeptine, we do know the outcome of it.

Before we launch in, you have to know how your mood is regulated. It’s done with serotonin. If you have adequate levels of serotonin, you’ll feel good, and if you don’t have enough, you’ll feel bad.

The easiest way to wrap your head around this is by considering the effects of a drug like MDMA. In essence, MDMA dumps serotonin out of your brain for 2-3 hours, and during that time, you feel on top of the world. But when you run out of serotonin, you crash, and you feel terrible for days after as your body tries to bring itself back to normal levels.

Okay, now, let’s launch into how it works.

Traditional antidepressants are usually SSRIs. SSRI stands for serotonin re-uptake inhibitor – basically, when your brain releases serotonin, these drugs try to get it out of your system as fast as possible. The thinking behind this is that your body will have to generate more serotonin to be able to function, and more serotonin being generated means a happier you in the long run.

However, tianeptine is actually a SSRE, which stands for serotonin re-uptake enhancer. Basically, when you take it, your body will try to hold onto as much serotonin as physically possible. The thinking behind this is that you will always have adequate serotonin levels, even if you’re not producing as much as you should be because of your depression.

Summary: tianeptine works by keeping as much serotonin in your body as possible.

Both are acceptable approaches, and SSRIs/SSREs work for many people. If you have depression and you’ve already tried a SSRIs, it’s definitely worth taking a look at a SSRE like tianeptine. If you’re healthy (no depression), you can try a SSRE to make yourself feel better all of the time.

Tianeptine dosing

Dosage varies based on your specific body composition. We can’t tell you exactly what dose will be optimal, but we can give you a jumping off point.

You’ll usually see pills for tianeptine in the 10mg to 15mg range. The most common is 12.5mg. We recommend taking two or three of these pills to start.

You can go a little bit higher than that if you’d like, but anything past 60mg per day is pushing it. Tianeptine puts your live under stress, and while under 60mg is no problem, anything past that can cause unpleasant side effects like dizziness, nausea, and even vertigo.

It’s sort of like Tylenol – taking it once a week is completely fine, but taking it every day or taking it over the recommended amount can be very harmful to your liver, and even fatal in some cases.

Other side effects from tianeptine

The positive one is putting you in a better mood, but users have reported some mild side effects that appear with that mood enhancement. This isn’t a big deal – all antidepressants have side effects, even prescribed SSRIs.

  • Dry mouth: make sure to keep a water bottle on hand while trying out tianeptine.
  • Irregular sleep patterns: some experience drowsiness, whereas others experience insomnia. This isn’t common, but pay attention to how your body reacts when you start your regimen.
  • Constipation, low blood pressure, and vivid dreams: these are the least common, and usually one-off occurrences when you first start taking tianeptine.

Tianeptine Summary

  • It’s an antidepressant that can be used by those suffering from depression
  • It works as a SSRE, not a SSRI
  • Optimal dosage is 12.5mg 2-3x per day – do not exceed 60mg per day without consulting a doctor first